| Company Name: |
Shanghai Han-Xiang Chemical Co., Ltd.
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| Tel: |
15971444841 |
| Email: |
amber@biochempartner.com |
| Products Intro: |
Product Name:Vedroprevir
CAS:1098189-15-1
Purity:98% HPLC LCMS Package:1KG;100KG
|
| Company Name: |
Taizhou Crene Biotechnology Co. Ltd.
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| Tel: |
0576-88813233 13396860566 |
| Email: |
sales@pharm-intermediates.com |
| Products Intro: |
Product Name:VEDROPREVIR ;GS-9451
CAS:1098189-15-1
Purity:98% HPLC Package:0.5G 1.0G 10G 1KG
|
| Company Name: |
Hubei Xinyang Medical Technology Co., Ltd
|
| Tel: |
15347293736 15347293736 |
| Email: |
2853117764@qq.com |
| Products Intro: |
Product Name:Vedroprevir
CAS:1098189-15-1
Purity:99% HPLC Package:10mg；25mg；50mg；100mg
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Vedroprevir
CAS:1098189-15-1
Purity:NULL Package:10mg;25mg Remarks:NULL
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| | GS 9451 Basic information |
| Product Name: | GS 9451 | | Synonyms: | (1R,2R)-N-[[(1alpha,3beta,5alpha)-Bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-cyclopropanecarboxylic acid;Vedroprevir;OTXAMWFYPMNDME-FQQWJMKMSA-N;Cyclopropanecarboxylic acid, N-[[(1α,3β,5α)-bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-, (1R,2R)- | | CAS: | 1098189-15-1 | | MF: | C45H60ClN7O9S | | MW: | 910.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1098189-15-1.mol |  |
| | GS 9451 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | pka | 5.10±0.50(Predicted) |
| | GS 9451 Usage And Synthesis |
| Uses | Vedroprevir is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion. |
| | GS 9451 Preparation Products And Raw materials |
| Raw materials | Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4R)?-?4-?[[8-?chloro-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?-?7-?[2-?(4-?morpholinyl)?ethoxy]?-?4-?quinolinyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?--->Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4R)?-?4-?[[8-?chloro-?7-?(2,?2-?dimethoxyethoxy)?-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?-?4-?quinolinyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?--->Cyclopropanecarboxyl?ic acid, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?(4S)?-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?--->4-?Quinolinol, 8-?chloro-?7-?(2,?2-?dimethoxyethoxy)?-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?--->Ethanone, 1-?[2-?amino-?3-?chloro-?4-?(2,?2-?dimethoxyethoxy)?phenyl]?--->Ethanone, 1-?(2-?amino-?3-?chloro-?4-?hydroxyphenyl)?--->Carbonic acid, (1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yl (2,?5-?dioxo-?1-?pyrrolidinyl) ester-->L-?Proline, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?, (4S)?--->L-Proline, 4-[[(4-bromophenyl)sulfonyl]oxy]-, methyl ester, hydrochloride (1:1), (4S)--->L-?Proline, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?, methyl ester, (4S)?--->CIS-BICYCLO[3.1.0]HEXAN-3-OL-->Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4S)?-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?--->Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)- |
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