| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:PK7242 maleate
CAS:1446352-68-6
Purity:95% Remarks:PK7242 is an inducer of reactivation of mutant p53 in cancer cells.
|
| Company Name: |
Pharmacodia (Beijing) Co.,Ltd
|
| Tel: |
+86-400-851-9921 |
| Email: |
sales@pharmacodia.com |
| Products Intro: |
Product Name:PK7242 Maleate
CAS:1446352-68-6
Package:10Mg-100g
|
| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
| Email: |
info@lynnchem.com |
| Products Intro: |
Product Name:PK7242 Maleate
CAS:1446352-68-6
Purity:95% Package:1mg;5mg
|
PK7242 Maleate manufacturers
- PK7242 (maleate)
-
- $268.00 / 1mg
-
2024-10-24
- CAS:
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | PK7242 Maleate Basic information |
| Product Name: | PK7242 Maleate | | Synonyms: | PK7242 Maleate;2-(4-(4-fluorophenyl)-3-(1H-pyrrol-1-yl)-1H-pyrazol-1-yl)-N,N-dimethylethanamine;2-[4-(4-fluorophenyl)-3-pyrrol-1-ylpyrazol-1-yl]-N,N-dimethylethanamine;1H-Pyrazole-1-ethanamine, 4-(4-fluorophenyl)-N,N-dimethyl-3-(1H-pyrrol-1-yl)-;2-[4-(4-Fluorophenyl)-3-(1-pyrrolyl)-1-pyrazolyl]-N,N-dimethylethanamine | | CAS: | 1446352-68-6 | | MF: | C17H19FN4 | | MW: | 298.36 | | EINECS: | | | Product Categories: | | | Mol File: | 1446352-68-6.mol |  |
| | PK7242 Maleate Chemical Properties |
| | PK7242 Maleate Usage And Synthesis |
| Description | The protein p53, often called the ''guardian of the genome,'' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. Its role as a tumor suppressor is evident by the observation that approximately 50% of human tumors have mutated or non-functional p53. PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In cancer cells carrying the Y220C mutant, PK7242 binds to the p53-Y220C core domain and induces growth inhibition, cell-cycle arrest, and apoptosis. |
| | PK7242 Maleate Preparation Products And Raw materials |
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