- Guggulsterone
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- $0.00 / 1kg
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2024-12-12
- CAS:95975-55-6
- Min. Order: 1kg
- Purity: 99% min
- Supply Ability: 20 tons
- Guggulsterone
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- $30.00 / 1mg
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2024-11-19
- CAS:95975-55-6
- Min. Order:
- Purity: 99.40%
- Supply Ability: 10g
- (Z)-Guggulsterone
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- $1.00 / 1kg
-
2019-07-06
- CAS:95975-55-6
- Min. Order: 1kg
- Purity: 95%-99%
- Supply Ability: 10kg
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| | (Z)-Guggulsterone Basic information |
| Product Name: | (Z)-Guggulsterone | | Synonyms: | 4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE;PREGNA-4,17(20)-DIENE-3,16-DIONE;(8S,9R,10R,13S,14S,17E)-17-(1-methoxyethylidene)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione;pregna-4,17-diene-3,16-dione;GUGGULISTERONES 95%;CIS-4,17(20)-PREGNADIENE-3,16-DIONE;CIS GUGGULSTERONE;GUGULSTERONE | | CAS: | 95975-55-6 | | MF: | C21H28O2 | | MW: | 312.45 | | EINECS: | 1308068-626-2 | | Product Categories: | Miscellaneous | | Mol File: | 95975-55-6.mol |  |
| | (Z)-Guggulsterone Chemical Properties |
| Boiling point | 463.3±45.0 °C(Predicted) | | density | 1.10±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 5 mg/mL | | form | powder | | color | light yellow | | CAS DataBase Reference | 95975-55-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 37 | | Safety Statements | 36 | | WGK Germany | 3 | | HS Code | 29147000 |
| | (Z)-Guggulsterone Usage And Synthesis |
| Uses | Guggulsterone is a broad spectrum steroid receptor ligand. Gum resin of Commiphora mukul marketed as an antihyperlipidemic drug. | | Definition | ChEBI: Guggulsterone is a 3-hydroxy steroid. It has a role as an androgen. | | Biological Activity | Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR). |
| | (Z)-Guggulsterone Preparation Products And Raw materials |
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