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| Product Name: | ML-299 | | Synonyms: | ML-299;4-bromo-N-[(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide;Benzamide, 4-bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]-;ML-299 (S)-4-bromo-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decanyl)propan-2-yl)benzamide;VU0463568 | | CAS: | 1426916-00-8 | | MF: | C23H26BrFN4O2 | | MW: | 489.38 | | EINECS: | | | Product Categories: | | | Mol File: | 1426916-00-8.mol |  |
| | ML-299 Chemical Properties |
| Boiling point | 708.8±60.0 °C(Predicted) | | density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml | | form | A crystalline solid | | pka | 14.02±0.46(Predicted) |
| | ML-299 Usage And Synthesis |
| Uses | ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2. It dose-dependently decreases the invasive migration of U87-MG glioblastoma cells into matrigel. | | storage | Store at -20°C |
| | ML-299 Preparation Products And Raw materials |
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