| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:INF 4E
CAS:88039-46-7
Purity:98% by HPLC Remarks:INF 4E is an inhibitor of caspase-1 and NLRP3 ATPase activities. It inhibits nigericin or ATP induced pyroptosis of PMA-differentiated and LPS-primed THP-1 cells, and activates the Keap1-Nrf2 pathway.
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| | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Basic information |
| Product Name: | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester | | Synonyms: | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester;Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate;INF 4E;inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells;Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester | | CAS: | 88039-46-7 | | MF: | C12H13ClO3 | | MW: | 240.68282 | | EINECS: | | | Product Categories: | | | Mol File: | 88039-46-7.mol |  |
| | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Chemical Properties |
| Boiling point | 180-185 °C(Press: 10 Torr) | | density | 1.222±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 12.51±0.20(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Usage And Synthesis |
| Uses | INF 4E was used to study the electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis. | | storage | Store at -20°C |
| | Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Preparation Products And Raw materials |
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