| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-PARP1
Purity:Prestige Antibodies P Package:100μL Remarks:HPA045168
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| | ANTI-PARP Basic information |
| Product Name: | ANTI-PARP | | Synonyms: | ANTI-PARP-1, BOVINE (RABBIT);ANTI-POLY(ADP-RIBOSE) POLYMERASE;ANTI-POLY(ADP-RIBOSE) POLYMERASE-1;ANTI-POLY(ADP-RIBOSE) POLYMERASE (AB-1), HUMAN;ANTI-POLY(ADP-RIBOSE) POLYMERASE (AB-1) RABBIT PAB;ANTI-POLY(ADP)-RIBOSE POLYMERASE (AB-3), BOVINE;ANTI-PARP;ANTI-PARP-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-PARP Structure]() |
| | ANTI-PARP Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-PARP Usage And Synthesis |
| Uses | Anti-poly (ADP-Ribose) polymerase is used for western blots, immunochemistry, immunofluorescence and immunoprecipitation. | | Uses | Monoclonal Anti-PARP (Cleaved-Asp214) antibody has been used in western blotting and immunohistochemical staining. | | General Description | Monoclonal Anti-PARP (mouse IgG1) is produced by immunizing mice with purified calf thymus poly (ADPribose) polymerase as the antigen. This antibody recognizes a 116kDa protein which corresponds to PARP and the 85kDa apoptosis induced cleavage product of prICE (proteinase resembling interleukin 1b-converting enzyme) and CPP32 (cysteine protease). It also recognizes PARP from mouse, rat, hamster and primate sources, but fails to detect avian PARP.
Poly (ADP-ribose) polymerase 1 (PARP1)/PARP is encoded by the gene mapped to human chromosome 1q42. It is a nuclear protein with molecular mass of 113kDa and is characterized with three functional domains. It belongs to the PARP superfamily. | | Biochem/physiol Actions | PARP1 poly(ADP-ribose) polymerase 1) and its enzymatic product PAR controls cellular processes like DNA repair, chromatin remodeling, transcription and cell death. PARP1 regulates transcription. PARP1 can induce or block homologous recombination (HR). |
| | ANTI-PARP Preparation Products And Raw materials |
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