LOXO-195 manufacturers
- LOXO-195
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- $2.00 / 1KG
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2020-01-08
- CAS:1350884-56-8
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100g , 1kg, 5kg , 50kg
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| | LOXO-195 Basic information |
| Product Name: | LOXO-195 | | Synonyms: | LOXO-195;LOXO195 R racemic;12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-;Selitrectinib(LOXO-195) Racemate;(6RS)-LOXO-195;Selitrectinib Racemate;(18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one;LOXO-195(3aR) | | CAS: | 1350884-56-8 | | MF: | C20H21FN6O | | MW: | 380.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1350884-56-8.mol |  |
| | LOXO-195 Chemical Properties |
| density | 1.51±0.1 g/cm3(Predicted) | | pka | 11.44±0.40(Predicted) |
| | LOXO-195 Usage And Synthesis |
| Description | LOXO-195 is an orally available, highly potent, and selective TRK kinase inhibitor designed to overcome drug resistance mediated by acquired mutations. Although responses to TRK inhibition can be dramatic and durable; however, eventually emergence of acquired resistance is found to be inevitable. |
| | LOXO-195 Preparation Products And Raw materials |
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