137004-80-9
中文名称 | 137004-80-9 |
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中文同义词 | 化合物 T12404 |
英文名称 | Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo- |
英文同义词 | Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-;CCK-A receptor inhibitor 1;CCK A receptor inhibitor 1,CCKA receptor inhibitor 1 |
CAS号 | 137004-80-9 |
分子式 | C25H35NO6S |
分子量 | 477.6135 |
EINECS号 | |
相关类别 | |
Mol文件 | 137004-80-9.mol |
结构式 |
137004-80-9 性质
沸点 | 705.1±60.0 °C(Predicted) |
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密度 | 1.187±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 4.47±0.10(Predicted) |
CCK-A receptor inhibitor 1 是一种缩胆囊素 A (cholecystokinin A, CCK-A) 受体抑制剂,IC50 为 340 nM。
IC50: 340 nM (CCK-A receptor)
CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains.