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H2N-PEG6-CH2COOtBu

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Company Name: 9i LLC
Tel: +18039569191
Email: MWan@NiNeiLab.com
Products Intro: Product Name:H2N-PEG6-CH2COOtBu
CAS:297162-50-6
Purity:min.97% Package:341USD/1 g Remarks:NA552
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:NH2-PEG6-C1-Boc；H2N-PEG6-CH2COOtBu
CAS:297162-50-6
Purity:98.00% Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Borenpharm Co., Ltd
Tel: 027-65563561 18717150066
Email: 3207347307@qq.com
Products Intro: Product Name:Amino-PEG6-t-butyl acetate
CAS:297162-50-6
Purity:95% Package:1g;388.45USD|5g;791.84USD
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:Amino-PEG6-t-butyl acetate
CAS:297162-50-6
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:NH2-PEG6-CH2COOtBu
CAS:297162-50-6
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
H2N-PEG6-CH2COOtBu Basic information
Product Name:H2N-PEG6-CH2COOtBu
Synonyms:H2N-PEG6-CH2COOtBu;NH2-PEG6-C1-Boc;NH2CH2CH2(OCH2CH2)5OCH2CO2-t-Bu;NH2-PEG6-CH2COOtBu;tert-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosanoate;NH-2-PEG6-C1-Boc,PROTAC Linkers,Inhibitor,NH2 PEG6 C1 Boc,inhibit,NH2PEG6C1Boc;H2N-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-amino-, 1,1-dimethylethyl ester
CAS:297162-50-6
MF:C18H37NO8
MW:395.48828
EINECS:
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Mol File:297162-50-6.mol
H2N-PEG6-CH2COOtBu Structure
H2N-PEG6-CH2COOtBu Chemical Properties
Boiling point 463.4±40.0 °C(Predicted)
density 1.065±0.06 g/cm3(Predicted)
pka8.74±0.10(Predicted)
Safety Information
MSDS Information
H2N-PEG6-CH2COOtBu Usage And Synthesis
Biological ActivityNH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
H2N-PEG6-CH2COOtBu Preparation Products And Raw materials
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