Company Name: |
Amatek Scientific Co. Ltd.
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Tel: |
0512-56316828 |
Email: |
info@amateksci.com |
Products Intro: |
Product Name:N3-PEG8-CH2COOtBu CAS:1984776-39-7 Purity:97% HPLC Package:1g;5g;25g;100g
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Company Name: |
Affinity(Wuhan)Ltd.
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Tel: |
15841022315 |
Email: |
sales@affinitytech.cn |
Products Intro: |
Product Name:Azido-PEG8-CH2COOH t-Bu Ester CAS:1984776-39-7 Purity:95% Package:1g;5g;10g;25g;100g
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| N3-PEG8-CH2COOtBu Basic information |
Product Name: | N3-PEG8-CH2COOtBu | Synonyms: | N3-PEG8-CH2COOtBu;Azido-PEG8-C-Boc;Azido-PEG8-CH2COOtBu;Azido-PEG8-CH2COOH t-Bu Ester;N3-PEG8-CH2COOtBu/3,6,9,12,15,18,21,24-Octaoxahexacosanoic acid, 26-azido-, 1,1-dimethylethyl ester | CAS: | 1984776-39-7 | MF: | C22H43N3O10 | MW: | 509.6 | EINECS: | | Product Categories: | | Mol File: | 1984776-39-7.mol | ![N3-PEG8-CH2COOtBu Structure](CAS/20211123/GIF/1984776-39-7.gif) |
| N3-PEG8-CH2COOtBu Chemical Properties |
| N3-PEG8-CH2COOtBu Usage And Synthesis |
Biological Activity | Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| N3-PEG8-CH2COOtBu Preparation Products And Raw materials |
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