| Company Name: |
Amatek Scientific Co. Ltd.
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| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:N3-PEG8-CH2COOtBu
CAS:1984776-39-7
Purity:97% HPLC Package:1g;5g;25g;100g
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| Company Name: |
Affinity（Wuhan）Ltd.
|
| Tel: |
15841022315 |
| Email: |
sales@affinitytech.cn |
| Products Intro: |
Product Name:Azido-PEG8-CH2COOH t-Bu Ester
CAS:1984776-39-7
Purity:95% Package:1g;5g;10g;25g;100g
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| | N3-PEG8-CH2COOtBu Basic information |
| Product Name: | N3-PEG8-CH2COOtBu | | Synonyms: | N3-PEG8-CH2COOtBu;Azido-PEG8-C-Boc;Azido-PEG8-CH2COOtBu;Azido-PEG8-CH2COOH t-Bu Ester;N3-PEG8-CH2COOtBu/3,6,9,12,15,18,21,24-Octaoxahexacosanoic acid, 26-azido-, 1,1-dimethylethyl ester | | CAS: | 1984776-39-7 | | MF: | C22H43N3O10 | | MW: | 509.6 | | EINECS: | | | Product Categories: | | | Mol File: | 1984776-39-7.mol |  |
| | N3-PEG8-CH2COOtBu Chemical Properties |
| | N3-PEG8-CH2COOtBu Usage And Synthesis |
| Biological Activity | Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | N3-PEG8-CH2COOtBu Preparation Products And Raw materials |
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