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| | MILBEMECTIN A4 Basic information |
| Product Name: | MILBEMECTIN A4 | | Synonyms: | milbemycinb-1;MILBEMECTIN A4;milbemectine a4;milbemycin A4;(25R)-25-Ethyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B;(6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B;Antibiotic B-41A4;Milbemycin α3 | | CAS: | 51596-11-3 | | MF: | C32H46O7 | | MW: | 542.7 | | EINECS: | | | Product Categories: | | | Mol File: | 51596-11-3.mol |  |
| | MILBEMECTIN A4 Chemical Properties |
| Melting point | 212-215° | | alpha | D20 +106° (c = 0.25 in acetone) | | Boiling point | 732.9±60.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | storage temp. | 0-6°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | pka | 12.46±0.70(Predicted) | | color | White to off-white | | EPA Substance Registry System | Milbemycin A4 (51596-11-3) |
| RIDADR | 2588 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | MILBEMECTIN A4 Usage And Synthesis |
| Description | Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide. | | Uses | Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3). | | Uses | Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels. | | Uses | Acaricide. | | Definition | ChEBI: Milbemycin A4 is a milbemycin. | | IC 50 | Macrolide |
| | MILBEMECTIN A4 Preparation Products And Raw materials |
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