Company Name: |
Amatek Scientific Co. Ltd.
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Tel: |
0512-56316828 |
Email: |
info@amateksci.com |
Products Intro: |
Product Name:Propargyl-PEG8-CH2CH2COOH CAS:1613752-50-3 Purity:97% HPLC Package:1g;5g;25g;100g
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Propargyl-PEG8-CH2CH2COOH manufacturers
- Propargyl-PEG9-acid
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- $0.00 / 1g
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2024-03-26
- CAS:1613752-50-3
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| Propargyl-PEG8-CH2CH2COOH Basic information |
Product Name: | Propargyl-PEG8-CH2CH2COOH | Synonyms: | Propargyl-PEG8-CH2CH2COOH;Propargyl-PEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxahentriacont-30-ynoic acid;Propargyl-PEG8-C2-COOH;4,7,10,13,16,19,22,25,28-Nonaoxahentriacont-30-ynoic acid | CAS: | 1613752-50-3 | MF: | C22H40O11 | MW: | 480.55 | EINECS: | | Product Categories: | | Mol File: | 1613752-50-3.mol | ![Propargyl-PEG8-CH2CH2COOH Structure](CAS/20211123/GIF/1613752-50-3.gif) |
| Propargyl-PEG8-CH2CH2COOH Chemical Properties |
Boiling point | 563.1±50.0 °C(Predicted) | density | 1.124±0.06 g/cm3(Predicted) | pka | 4.28±0.10(Predicted) |
| Propargyl-PEG8-CH2CH2COOH Usage And Synthesis |
Biological Activity | Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Propargyl-PEG8-CH2CH2COOH Preparation Products And Raw materials |
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