Company Name: |
GL Biochem (Shanghai) Ltd
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Tel: |
21-61263452 13641803416 |
Email: |
ymbetter@glbiochem.com |
Products Intro: |
Product Name:rec IL-1ra (human) Purity:95% HPLC,98% HPLC Package:10mg, 25mg, 50mg, 100mg, 500mg, 1g,10g
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Company Name: |
Chemsky (shanghai) International Co.,Ltd
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Tel: |
021-50135380 |
Email: |
shchemsky@sina.com |
Products Intro: |
Product Name:rec IL-1ra (huMan); ;rec Interleukin-1 receptor antagonist (huMan) Purity:99% Package:5.0μg
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Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:IL-1Ra human Purity:recombinant, expressed in E. coli, >=98% (SDS-PAGE), >=98% ( Package:100UG Remarks:SRP3084-100UG
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| REC IL-1RA (HUMAN) Basic information |
Product Name: | REC IL-1RA (HUMAN) | Synonyms: | IL-1RA, HUMAN;INTERLEUKIN 1 RECEPTOR ANTAGONIST;HUMAN IL-1RA;REC INTERLEUKIN-1 RECEPTOR ANTAGONIST (HUMAN);REC IL-1RA (HUMAN);Mouse Interleukin 1 receptor antagonist elisa kit | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | ![REC IL-1RA (HUMAN) Structure]() |
| REC IL-1RA (HUMAN) Chemical Properties |
| REC IL-1RA (HUMAN) Usage And Synthesis |
General Description | The gene IL-1RA (interleukin-1 receptor antagonist) is mapped to human chromosome 2q. It belongs to the IL-1 (interleukin 1) family of proteins. The encoded protein has a TIR (Toll/IL-1 receptor) domain. IL-1RA is produced by corneal epithelial cells, monocytes, neutrophils, macrophages and fibroblasts. It is a naturally occurring inflammatory inhibitor protein. Recombinant human IL-1RA is a 17.2kDa protein consisting of 153 amino acid residues. | Biochem/physiol Actions | Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α (interleukin 1 α) and IL-1β (interleukin 1 β) by competitively blocking binding to their type I and type II receptors. Therapeutically, IL-1RA may help in the treatment of sepsis, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Low production of IL-1RA is observed in HIV-1 (human immunodeficiency virus 1)-infected dendritic cells. |
| REC IL-1RA (HUMAN) Preparation Products And Raw materials |
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