Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:UBP 296;(RS)-1-(2-AMino-2-carboxyethyl)-3-(2-carboxybenzyl)pyriMidine-2,4-dione Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
BOC Sciences
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Tel: |
1-631-485-4226; 16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:UBP 296 CAS:745055-86-1 Purity:98% by HPLC Remarks:UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1.09 μM) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:UBP 296 CAS:745055-86-1 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE manufacturers
- UBP 296
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- $723.00 / 10mg
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2024-10-24
- CAS:745055-86-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Basic information |
| (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Chemical Properties |
Melting point | 190.8-191.2 °C (decomp)(Solv: water (7732-18-5)) | Boiling point | 603.0±65.0 °C(Predicted) | density | 1.525±0.06 g/cm3(Predicted) | storage temp. | Store at RT | solubility | <3.33mg/ml in 1eq. NaOH; <3.33mg/ml in DMSO | pka | 2.12±0.10(Predicted) |
| (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Usage And Synthesis |
Uses | UBP 296 is a novel, potent and selective kainate receptor antagonist. | Definition | ChEBI: 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid is an alpha-amino acid. | Biological Activity | Selective and potent GluR5-subunit containing kainate receptor antagonist (apparent K D = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres. | storage | Store at RT |
| (RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE Preparation Products And Raw materials |
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