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BOC Sciences
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Products Intro: |
Product Name:TP-472 CAS:2079895-62-6 Purity:98% Package:1G;10G;100G Remarks:TP-472 is an inhibitor of bromodomain BRD9 and BRD7 bromodomain with Kd values of 33 and 340 nM, respectively.
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Product Name: | TP-472 | Synonyms: | TP-472;TP472,TP 472;Benzamide, 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl- | CAS: | 2079895-62-6 | MF: | C20H19N3O2 | MW: | 333.38 | EINECS: | | Product Categories: | | Mol File: | 2079895-62-6.mol | ![TP-472 Structure](CAS/20210111/GIF/2079895-62-6.gif) |
| TP-472 Chemical Properties |
density | 1.31±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: Soluble | form | A solid | pka | 14.98±0.20(Predicted) |
| TP-472 Usage And Synthesis |
Description | TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM; EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic Consortium (SGC) website for more information. | storage | Store at -20°C |
| TP-472 Preparation Products And Raw materials |
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