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BGC 20-1531 (hydrochloride)

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BGC 20-1531 (hydrochloride) Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:BGC-20-1531 hydrochloride(1186532-61-5 free base)
CAS:1962928-26-2
Purity:99.85% Package:1mg;133USD|2mg;198USD|5mg;298USD
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:BGC 20-1531 (hydrochloride)
CAS:1962928-26-2
Purity:95.0% windy 1058
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:BGC20-1531
CAS:1962928-26-2
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:BGC-20-1531 hydrochloride(1186532-61-5 free base)；BGC-20-1531 hydrochloride;AP-1531 hydrochloride;GTPL3380 hydrochloride
CAS:1962928-26-2
Package:1 mg；10 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:BGC 20-1531 (hydrochloride)
CAS:1962928-26-2
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

BGC 20-1531 (hydrochloride) manufacturers
BGC 20-1531 (hydrochloride) Basic information
Product Name:BGC 20-1531 (hydrochloride)
Synonyms:BGC 20-1531 (hydrochloride);AP 1531;BGC20-1531 (PGN-1531;4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide hydrochloride;GTPL3380 hydrochloride;AP-1531 hydrochloride;BGC201531 hydrochloride(1186532615 free base),BGC 20 1531 hydrochloride(1186532 61 5 free base)
CAS:1962928-26-2
MF:C26H25ClN2O6S
MW:529
EINECS:
Product Categories:
Mol File:1962928-26-2.mol
BGC 20-1531 (hydrochloride) Structure
BGC 20-1531 (hydrochloride) Chemical Properties
storage temp. Store at -20°C
solubility DMF: 1 mg/ml; DMSO: 1 mg/ml
form A crystalline solid
Safety Information
MSDS Information
BGC 20-1531 (hydrochloride) Usage And Synthesis
DescriptionBGC 20-1531 is a potent and selective antagonist of the prostaglandin E2 (PGE2; ) receptor subtype 4 (EP4) with Ki values of 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively. It is selective for EP4, exhibiting <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors at a concentration of 10 μM. BGC 20-1531 antagonizes PGE2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA cells that stably express human EP4 receptors. It also reverses PGE2-induced vasorelaxation (Kb = 15.85 nM) in human middle cerebral and middle meningeal arterial rings. BGC 20-1531 prevents PGE2-induced increases in carotid blood flow and decreases in carotid resistance with an ID50 value of 5 mg/kg in dogs.
UsesBGC 20-1531 Hydrochloride, is a potent and selective EP4 antagonist, exhibiting <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors at a concentration of 10 μM. It also Inhibits PGE2-induced vasodilation of middle cerebral and meningeal arterieshuman middle cerebral and middle meningeal arterial rings.
storageDesiccate at RT
BGC 20-1531 (hydrochloride) Preparation Products And Raw materials
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