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Shanghai Chaolan Chemical Technology Center
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QQ:65489617 15618227136 |
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Sales@ATKchemical.com |
| Products Intro: |
Product Name:PF-06446846
CAS:1632250-49-7
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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PF-06446846 manufacturers
- PF-06446846
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- $56.00 / 1mg
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2024-11-07
- CAS:1632250-49-7
- Min. Order:
- Purity: 99.4%
- Supply Ability: 10g
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| | PF-06446846 Basic information |
| Product Name: | PF-06446846 | | Synonyms: | PF-06446846;PF-6446846;Threonine proteases,PF06446846,Inhibitor,80S ribosome,Selective,PF 06446846,Ser/Thr Protease,Serine proteases,Rat bone marrow,Huh7,inhibit,Serine endopeptidases,PF-06446846;(R)-4-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide;Benzamide, N-(3-chloro-2-pyridinyl)-N-(3R)-3-piperidinyl-4-(3H-1,2,3-triazolo[4,5-b]pyridin-3-yl)- | | CAS: | 1632250-49-7 | | MF: | C22H20ClN7O | | MW: | 433.89 | | EINECS: | | | Product Categories: | | | Mol File: | 1632250-49-7.mol |  |
| | PF-06446846 Chemical Properties |
| Boiling point | 655.5±65.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 87 mg/mL (200.51 mM);Ethanol: 87 mg/mL (200.51 mM) | | pka | 8.69±0.10(Predicted) | | Water Solubility | Water: Insoluble |
| | PF-06446846 Usage And Synthesis |
| Definition | ChEBI: PF-06446846 is a triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9. It has a role as an antilipemic drug and an EC 3.4.21.61 (kexin) inhibitor. It is a monochloropyridine, a member of piperidines, a tertiary carboxamide, a member of benzamides and a triazolopyridine. |
| | PF-06446846 Preparation Products And Raw materials |
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