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BOC Sciences
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Product Name:VU 0463271
CAS:1391737-01-1
Purity:98% by HPLC Remarks:VU 0463271 is a potent and selective inhibitor of KCC2, which is a neuronal K-Cl cotransporter (IC50 = 61 nM). VU 0463271 exhibits >100-fold selectivity versus the Na-K-2Cl cotransporter 1 (NKCC1) and
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| | VU 0463271 Basic information |
| Product Name: | VU 0463271 | | Synonyms: | VU 0463271;VU0463271 (Synonyms: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide);N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide;VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide);Acetamide, N-cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-;Inhibitor,KcsA,VU0463271,Potassium Channel,VU 0463271,VU-0463271,inhibit | | CAS: | 1391737-01-1 | | MF: | C19H18N4OS2 | | MW: | 382.5 | | EINECS: | | | Product Categories: | | | Mol File: | 1391737-01-1.mol |  |
| | VU 0463271 Chemical Properties |
| storage temp. | 2-8°C | | solubility | Soluble in DMSO | | form | powder | | color | off-white to blue-gray |
| | VU 0463271 Usage And Synthesis |
| Uses | VU 0463271 is a novel antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2). | | storage | Store at +4°C |
| | VU 0463271 Preparation Products And Raw materials |
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