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BOC Sciences
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Product Name:VU 0463271 CAS:1391737-01-1 Purity:98% by HPLC Remarks:VU 0463271 is a potent and selective inhibitor of KCC2, which is a neuronal K-Cl cotransporter (IC50 = 61 nM). VU 0463271 exhibits >100-fold selectivity versus the Na-K-2Cl cotransporter 1 (NKCC1) and
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| VU 0463271 Basic information |
Product Name: | VU 0463271 | Synonyms: | VU 0463271;VU0463271 (Synonyms: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide);N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide;VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide);Acetamide, N-cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-;Inhibitor,KcsA,VU0463271,Potassium Channel,VU 0463271,VU-0463271,inhibit | CAS: | 1391737-01-1 | MF: | C19H18N4OS2 | MW: | 382.5 | EINECS: | | Product Categories: | | Mol File: | 1391737-01-1.mol | ![VU 0463271 Structure](CAS/20200515/GIF/1391737-01-1.gif) |
| VU 0463271 Chemical Properties |
storage temp. | 2-8°C | solubility | Soluble in DMSO | form | powder | color | off-white to blue-gray |
| VU 0463271 Usage And Synthesis |
Uses | VU 0463271 is a novel antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2). | storage | Store at +4°C |
| VU 0463271 Preparation Products And Raw materials |
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