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| 3-Ethyl-4-methyl-3-pyrrolin-2-one Basic information |
| 3-Ethyl-4-methyl-3-pyrrolin-2-one Chemical Properties |
Melting point | 100-104 °C (lit.) | Boiling point | 279.0±23.0 °C(Predicted) | density | 0.977±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | solubility | Chloroform (Slightly), Methanol (Slightly) | form | powder to crystal | pka | 14.44±0.60(Predicted) | color | White to Almost white | Water Solubility | Slightly soluble in water. | CAS DataBase Reference | 766-36-9(CAS DataBase Reference) |
Hazard Codes | Xi | Safety Statements | 22-24/25 | WGK Germany | 3 | Hazard Note | Irritant | HS Code | 29337900 |
| 3-Ethyl-4-methyl-3-pyrrolin-2-one Usage And Synthesis |
Uses | 3-Ethyl-4-methyl-3-pyrrolin-2-one is used as an intermediate for the manufacture of medicines. It is used for the preparation of Glimepiride (G410150), and its intermediates and as antidiabetic agents. | General Description | 3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:
- allylamine, via palladium(II)-assisted cyclization
- 4-methoxybenzylamine, via a ring-closing-metathesis strategy
- 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one
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| 3-Ethyl-4-methyl-3-pyrrolin-2-one Preparation Products And Raw materials |
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