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MMP-3 INHIBITOR VIII

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MMP-3 INHIBITOR VIII Suppliers list
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:MMP3 inhibitor 2
CAS:208663-26-7
Purity:NLT 98% Remarks:MC539071
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:MMP-3 Inhibitor VIII
CAS:208663-26-7
Purity:>=98% Package:$380.9/5mg;Bulk package Remarks:98%
Company Name: VDM Biochemicals   
Tel: 0330-2528181
Email: sales@vdmbio.com
Products Intro: Product Name:MMP-3 Inhibitor VIII
CAS:208663-26-7
Purity:>=98%
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Products Intro: Product Name:MMP-3 Inhibitor VIII
CAS:208663-26-7
Purity:95% Remarks:MMP-3 inhibitor VIII is a cell-permeable inhibitor of matrix metalloproteinase-3 (MMP-3) with Ki value of 23 nM. It also inhibits mouse macrophage metalloelastase MME/MMP-12.
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:MMP-3 Inhibitor VIII
CAS:208663-26-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
MMP-3 INHIBITOR VIII Basic information
Product Name:MMP-3 INHIBITOR VIII
Synonyms:MMP-3 INHIBITOR VIII;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-;MMP3 inhibitor 2
CAS:208663-26-7
MF:C20H26N2O5S
MW:406.5
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Mol File:Mol File
MMP-3 INHIBITOR VIII Structure
MMP-3 INHIBITOR VIII Chemical Properties
density 1.245±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka9.13±0.40(Predicted)
Safety Information
MSDS Information
MMP-3 INHIBITOR VIII Usage And Synthesis
DescriptionMatrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.
MMP-3 INHIBITOR VIII Preparation Products And Raw materials
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