| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:TC-E 5008
CAS:50405-58-8
Remarks:TC-E 5008 is a selective and cancer-associated mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor (Ki = 120-190 nM), displaying >60-fold selectivity for mIDH1 (found in ~75% of gliomas) over wild typ
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| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
|
| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:TC-E 5008
CAS:50405-58-8
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone manufacturers
- TC-E 5008
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- $2500.00 / 100mg
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2024-10-24
- CAS:50405-58-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Basic information |
| | 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Usage And Synthesis |
| Uses | TC-E 5008 is a cancer-assocaited mutant isocitrate dehydrogenase inhibitor, which was found to be permeable through the blood-brain barrier. | | Definition | ChEBI: SYC-435 is a cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and benzyl groups, respectively. It is a potent inhibitor of mutant isocitrate dehydrogenase 1 (Ki values of 190 nM against R132H mutant and 120 nM against R132C mutant). It has a role as an EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor and an antineoplastic agent. It is a member of benzenes, a pyridone and a cyclic hydroxamic acid. |
| | 1-Hydroxy-4-methyl-6-(phenylmethyl)-2-(1H)pyridinone Preparation Products And Raw materials |
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