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GKK1032B

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GKK1032B Suppliers list
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:GKK1032B
CAS:358375-11-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:GKK1032B
CAS:358375-11-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Company Name: Beijing Biocreative Technology Co., Ltd.  
Tel: 15522676233
Email: 3007606172@qq.com
Products Intro: Product Name:GKK1032B
CAS:358375-11-8
Purity:>70% Package:1mg
Company Name: Nanjing Tengyi Biotechnology Co., Ltd  
Tel: 025-58851786 17714337195
Email: sales@tybiochem.com
Products Intro: Product Name:(3aR,9aR,9bS,10R,12S,13aR,13bR,13cR,16R,16aS,17aS)-rel-(+)-16-ethenyl-3a,9b,10,11,12,13,13a,13b,13c,16,16a,17a-dodecahydro-10,12,13a,14,16-pentamethyl-5,8-ethenofluoreno[9',1':2,3,4]oxacyclododecino[6,7-c]pyrrole-1,3,17(2H,4H,9aH)-trione
CAS:358375-11-8
Purity:95+% Package:1g;5g
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:GKK1032B
CAS:358375-11-8
Purity:70% Package:1mg
GKK1032B Basic information
Product Name:GKK1032B
Synonyms:GKK1032B;5,8-Ethenofluoreno[9',1':2,3,4]oxacyclododecino[6,7-c]pyrrole-1,3,17(2H,4H,9aH)-trione, 16-ethenyl-3a,9b,10,11,12,13,13a,13b,13c,16,16a,17a-dodecahydro-10,12,13a,14,16-pentamethyl-, (3aR,9aR,9bS,10R,12S,13aR,13bR,13cR,16R,16aS,17aS)-rel-(+)-;(3aR,9aR,9bS,10R,12S,13aR,13bR,13cR,16R,16aS,17aS)-rel-(+)-16-ethenyl-3a,9b,10,11,12,13,13a,13b,13c,16,16a,17a-dodecahydro-10,12,13a,14,16-pentamethyl-5,8-ethenofluoreno[9',1':2,3,4]oxacyclododecino[6,7-c]pyrrole-1,3,17(2H,4H,9aH)-trione
CAS:358375-11-8
MF:C32H39NO4
MW:501.66
EINECS:
Product Categories:
Mol File:Mol File
GKK1032B Structure
GKK1032B Chemical Properties
Boiling point 653.9±55.0 °C(Predicted)
density 1.130±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Dichloromethane: soluble; DMSO: soluble; Ethanol: soluble
form A solid
pka8.99±0.70(Predicted)
Safety Information
MSDS Information
GKK1032B Usage And Synthesis
DescriptionGKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. subtilis and M. tuberculosis.
in vitroAmong them, GKK1032B showed significant cytotoxicity against human osteosarcoma cell line MG63 with an IC50 value of 3.49 μmol·L-1, and a primary mechanistic study revealed that it induced the apoptosis of MG63 cellsvia caspase pathway activation._x000D_ _x000D_ Reference: Chin J Nat Med. 2022 Jan;20(1):67-73. https://pubmed.ncbi.nlm.nih.gov/35101251/
targetGKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation.
GKK1032B Preparation Products And Raw materials
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