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BOC Sciences
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Product Name:Drimendiol
CAS:34437-62-2
Purity:>95% by HPLC Remarks:Drimendiol is a polyploid sesquiterpene diol, which is reported to be a quorum sensing inhibitor.
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:Drimendiol
CAS:34437-62-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:Drimendiol
CAS:34437-62-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | Drimendiol Basic information |
| Product Name: | Drimendiol | | Synonyms: | Drimendiol;1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-, (1R,4aS,8aS)-;(1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1,2-naphthalenedimethanol;((1r,4As,8as)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalene-1,2-diyl)dimethanol | | CAS: | 34437-62-2 | | MF: | C15H26O2 | | MW: | 238.37 | | EINECS: | | | Product Categories: | | | Mol File: | 34437-62-2.mol |  |
| | Drimendiol Chemical Properties |
| Melting point | 73.5-74.5 °C | | Boiling point | 352.7±17.0 °C(Predicted) | | density | 0.993±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | A solid | | pka | 14.82±0.10(Predicted) |
| | Drimendiol Usage And Synthesis |
| Description | Drimendiol is a sesquiterpene that has been found in W. ugandensis.1 It inhibits C. albicans, S. aureus, and S. epidermidis biofilm formation with 50% biofilm inhibitory concentration values (BIC50s) of 25.5, 65.1, and 67.1 μg/ml, respectively. It has antifouling activity, inhibiting the settlement of C. savignyi and B. improvisus larvae on a petri dish surface (EC50s = 1 and 0.5 μg/ml, respectively).2 | | Definition | ChEBI: Drimendiol is a member of the class of octahydronaphthalenes that is drimenol in which a hydrogen of the allylic methyl group has been replaced by a hydroxy group. It has a role as a quorum sensing inhibitor and a plant metabolite. It is a member of octahydronaphthalenes, a sesquiterpenoid, a homoallylic alcohol and an allylic alcohol. It is functionally related to a drimenol. It derives from a hydride of a drimane. | | References | 1. Kipanga, P.N., Liu, M., Panda, S.K., et al. Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms J. Ethnopharmacol. 248:112352,(2020).
2. Moodie, L.W., Trepos, R., Cervin, G., et al. Probing the structure-activity relationship of the natural antifouling agent polygodial against both micro- and macrofoulers by semisynthetic modification J. Nat. Prod. 80(2),515-525(2017). |
| | Drimendiol Preparation Products And Raw materials |
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