INDEX NAME NOT YET ASSIGNED manufacturers
- SJF 1521
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- $615.00 / 1mg
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2024-10-28
- CAS:2230821-40-4
- Min. Order:
- Purity: 99.20%
- Supply Ability: 10g
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| | INDEX NAME NOT YET ASSIGNED Basic information |
| Product Name: | INDEX NAME NOT YET ASSIGNED | | Synonyms: | SJF 1521;(2S,4R)-1-[(2S)-2-(2-{2-[2-(2-{4-[4-({3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}amino)quinazolin-6-yl]phenoxy}ethoxy)ethoxy]ethoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide | | CAS: | 2230821-40-4 | | MF: | C57 H61 Cl F N7 O9 S | | MW: | 1074.66 | | EINECS: | | | Product Categories: | | | Mol File: | 2230821-40-4.mol |  |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| Boiling point | 1160.1±65.0 °C(Predicted) | | density | 1.314±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO|107.47|100| | | pka | 13.54±0.46(Predicted) | | form | Solid | | color | Light green to yellow |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Description | SJF 1521 is a selective EGFR PROTAC?? Degrader based on the EGFR inhibitor lapatinib linked to a von Hippel-Lindau (VHL) recruiting ligand by PEG3. SJF 1521 exhibits selectivity for EGFR, including mutant forms, over HER2 and induces degradation of EGFR in OVCAR8 cells. | | storage | Store at -20°C |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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