| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Fluorinated VHL Spy Molecule 4
CAS:2290526-31-5
Purity:Fluorinated VHL Spy Molecule 4 Package:10MG Remarks:909459-10MG
|
| Company Name: |
ShangHai Biochempartner Co.,Ltd
|
| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Fluorinated VHL Spy Molecule 4
CAS:2290526-31-5
Purity:98% HPLC LCMS Package:100MG;1G
|
| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:Fluorinated VHL Spy Molecule 4
CAS:2290526-31-5
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G,500G
|
| Company Name: |
Jilin Province Woda Biotechnology Co., Ltd.
|
| Tel: |
13504435624 |
| Email: |
1927928688@qq.com |
| Products Intro: |
Product Name:(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide
CAS:2290526-31-5
Purity:99% HPLC Package:1克;5克;
|
|
| | Fluorinated VHL Spy Molecule 4 Basic information |
| Product Name: | Fluorinated VHL Spy Molecule 4 | | Synonyms: | Fluorinated VHL Spy Molecule 4;2-Pyrrolidinecarboxamide, N-[(4-bromophenyl)methyl]-4-hydroxy-1-(3,3,3-trifluoro-1-oxopropyl)-, (2S,4R)-;(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(3,3,3-trifluoropropanoyl)pyrrolidine-2-carboxamide | | CAS: | 2290526-31-5 | | MF: | C15H16BrF3N2O3 | | MW: | 409.2 | | EINECS: | | | Product Categories: | | | Mol File: | 2290526-31-5.mol |  |
| | Fluorinated VHL Spy Molecule 4 Chemical Properties |
| Boiling point | 595.3±50.0 °C(Predicted) | | density | 1.586±0.06 g/cm3(Predicted) | | pka | 14.02±0.40(Predicted) |
| | Fluorinated VHL Spy Molecule 4 Usage And Synthesis |
| Uses | Fluorinated VHL Spy Molecule 4 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909416, 909432, and 909440.
The E3 ligase VHL is of growing interest for targeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders. |
| | Fluorinated VHL Spy Molecule 4 Preparation Products And Raw materials |
|