Log in | Join Free | china | japan | germany

5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)-

Request For Quotation
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:TSHR antagonist S37b
CAS:2143452-22-4
Purity:95% Package:2mg;5mg;25mg
Company Name: Shanghai?Medlife?Pharm-Tech?Co.,?Ltd  
Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Products Intro: Product Name:TSHR antagonist S37b
CAS:2143452-22-4
Purity:>=99% Package:50mg;10mg;10mM*1mLinDMSO;25mg;500mg;200mg;5mg;100mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:TSHR antagonist S37b
CAS:2143452-22-4
Package:2mg/RMB 3420;5mg/RMB 3990;25mg/RMB 15300
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Basic information
Product Name:5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)-
Synonyms:5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)-;TSHR antagonist S37b;TSHR antagonist S37b,TSHR antagonist S-37b
CAS:2143452-22-4
MF:C25H20N2O3S2
MW:460.57
EINECS:
Product Categories:
Mol File:2143452-22-4.mol
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Structure
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Chemical Properties
density 1.54±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (217.12 mM; Need ultrasonic)
pka9.16±0.40(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Usage And Synthesis
Biological ActivityTSHR antagonist S37b is the less effective enantiomer of TSHR antagonist S37a . TSHR antagonist S37b shows only a minor effect for thyrotropin receptor (TSHR) inhibition. TSHR antagonist S37b can be used for the research of thyroid function[1].
References[1]. Marcinkowski P, et al. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves’ Orbitopathy. Thyroid. 2019 Jan;29(1):111-123.
5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)- Preparation Products And Raw materials
Tag:5,9-Methanothiazolo[5',4':5,6]thiopyrano[2,3-f]isoindole-2,6,8(7H)-trione, 3,4a,5,5a,8a,9,9a,10-octahydro-7,10-diphenyl-, (4aR,5R,5aS,8aS,9S,9aR,10S)-(2143452-22-4) Related Product Information