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Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester

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Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:RO-5328673
CAS:1310817-94-7
Purity:0 Package:100mg/RMB 25500;50mg/RMB 19800;25mg/RMB 15000
Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Basic information
Product Name:Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester
Synonyms:Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester;RO-5328673
CAS:1310817-94-7
MF:C29H32Cl2FN3O4
MW:576.49
EINECS:
Product Categories:
Mol File:1310817-94-7.mol
Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Structure
Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Chemical Properties
Boiling point 716.6±60.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
pka-1.08±0.40(Predicted)
Safety Information
MSDS Information
Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Usage And Synthesis
DescriptionRO-5328673 is a dual NK2/NK3 antagonist. O5328673. [(3)H]RO5328673 bound to a single saturable site on hNK2, hNK3 and gpNK3 with high-affinity. RO5328673 acted as an insurmountable antagonist at both human and guinea-pig NK3 receptors in the [(3)H]IP accumulation assay. In binding kinetic analyses, [(3)H]RO5328673 had fast association and dissociation rates at hNK2 while it had a fast association rate and a remarkably slow dissociation rate at gp and hNK3. In electrophysiological recordings of gp SNpc, RO5328673 inhibited the senktide-induced potentiation of spontaneous activity of dopaminergic neurons with an insurmountable mechanism of action. RO5328673 exhibited in-vivo activity in gerbils, robustly reversing the senktide-induced locomotor activity.
Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester Preparation Products And Raw materials
Tag:Carbamic acid, N-[(3S,4R)-4-(3,4-dichlorophenyl)-1-[[1-[(1-methylcyclopropyl)carbonyl]-4-piperidinyl]carbonyl]-3-pyrrolidinyl]-N-methyl-, 4-fluorophenyl ester(1310817-94-7) Related Product Information