Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)-

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:EAAT2 activator 1 CAS:892415-28-0 Purity:98.86% Package:5mg;33USD\|10mg;58USD\|25mg;119USD

Company Name:	TargetMol Chemicals Inc.
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Email:	support@targetmol.com
Products Intro:	Product Name:EAAT2 activator 1；3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine CAS:892415-28-0 Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	SUZHOU SENFEIDA CHEMICAL CO.,LTD
Tel:	+86-0512-83500002 +8615195660023
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Products Intro:	Product Name:ω- transaminase CAS:892415-28-0 Purity:0.99 Package:200kg

Company Name:	Aladdin Scientific
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Email:	tp@aladdinsci.com
Products Intro:	Product Name:EAAT2 activator 1 CAS:892415-28-0 Purity:98% Package:$70.9/5mg;$120.9/10mg;$250.9/25mg;$450.9/50mg;$750.9/100mg;Bulk package Remarks:98%

Company Name:	Tianjin Kailiqi Biotechnology Co., Ltd.
Tel:	15076683720
Email:	klq@cw-bio.com
Products Intro:	Product Name:EAAT2 activator 1 CAS:892415-28-0 Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- manufacturers

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- Basic information

Product Name:	Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)-
Synonyms:	Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)-;EAAT2 activator 1;3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine;F2005-0304;GLT-1,Excitatory amino acid transporter 2,inhibit,Glutamate transporter 1,Inhibitor,EAAT-2 activator 1,EAAT2 activator 1,EAAT2,glutamate transporter,synapse;ω- transaminase;EAAT2 activator 1, 10 mM in DMSO
CAS:	892415-28-0
MF:	C16H11ClFN3S
MW:	331.8
EINECS:
Product Categories:
Mol File:	892415-28-0.mol

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- Chemical Properties

Boiling point	527.6±50.0 °C(Predicted)
density	1.41±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 25 mg/mL (75.35 mM; ultrasonic and warming and heat to 60°C)
pka	0.65±0.19(Predicted)
form	Solid
color	Light brown to brown

Safety Information

MSDS Information

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- Usage And Synthesis

Uses	EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently[1].
Biological Activity	EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently[1].
IC 50	EAAT2
References	[1]. Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011;21(19):5774-5777.

Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)- Preparation Products And Raw materials

Tag:Pyridazine, 3-[[(2-chloro-6-fluorophenyl)methyl]thio]-6-(2-pyridinyl)-(892415-28-0) Related Product Information

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