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2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-

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2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Suppliers list
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:BCL6-IN-4
CAS:2253879-65-9
Purity:98% Package:$500.9/5mg;$850.9/10mg;$1800.9/25mg;$3000.9/50mg;$4600.9/100mg;Bulk package Remarks:98%
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:BCL6-IN-4
CAS:2253879-65-9
Package:100mg;3700USD|50mg;2480USD|25mg;1900USD
Company Name: Hefei fuya biotechnology co. LTD  
Tel: 18096409024
Email: sales02@foreversyn.com
Products Intro: Product Name:2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-
CAS:2253879-65-9
Purity:95% HPLC Package:1G;100G
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:BCL6-IN-4
CAS:2253879-65-9
Package:5mg/RMB 4160;25mg/RMB 15000;50mg/RMB 19800
Company Name: Shanghai Yiyan Biotechnology Co. , Ltd.  
Tel: 021-69985186 13611928337
Email: 3427709316@qq.com
Products Intro: Product Name:BCL6-IN-4
CAS:2253879-65-9

2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- manufacturers

  • BCL6-IN-4
  • BCL6-IN-4 pictures
  • $3700.00 / 100mg
  • 2024-10-28
  • CAS:2253879-65-9
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Basic information
Product Name:2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-
Synonyms:2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-;BCL6-IN-4;BCL-6-IN-4,BCL6 IN 4,BCL6IN4
CAS:2253879-65-9
MF:C25H35ClN6O3
MW:503.04
EINECS:
Product Categories:
Mol File:2253879-65-9.mol
2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Structure
2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Chemical Properties
Boiling point 647.3±65.0 °C(Predicted)
density 1.237±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 73.33 mg/mL (145.77 mM; Need ultrasonic)
pka15.14±0.29(Predicted)
form Solid
color White to light brown
Safety Information
MSDS Information
2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Usage And Synthesis
Biological ActivityBCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC50 of 97 nM. BCL6-IN-4 has anti-tumor activities[1]. BCL6-IN-4 (compound 25b) inhibits OCI-Ly1 and OCI-Ly3 cell lines growth with GI50 values of 2.8 μM and 4.2 μM, respectively[1].
References[1]. Benjamin R Bellenie, et al. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J Med Chem. 2020 Apr 23;63(8):4047-4068.
2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl- Preparation Products And Raw materials
Tag:2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-(2253879-65-9) Related Product Information