Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:NCT02 CAS:790245-61-3 Purity:98% Package:200 mg
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| 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)- Basic information |
Product Name: | 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)- | Synonyms: | 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)-;2-{5h,6h,7h-indeno[5,6-b]furan-3-yl}-n-(5-methyl-1,3-thiazol-2-yl)acetamide;NCT02 | CAS: | 790245-61-3 | MF: | C17H16N2O2S | MW: | 312.39 | EINECS: | | Product Categories: | | Mol File: | 790245-61-3.mol | |
| 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)- Chemical Properties |
density | 1.368±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble to 100 mM in DMSO | pka | 8.95±0.50(Predicted) | form | Solid | color | Light yellow to light brown |
| 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)- Usage And Synthesis |
Biological Activity | NCT02 is a cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12. NCT02 has the potential for the research of metastatic colorectal cancer (CRC)[1]. | storage | Store at -20°C | References | [1]. Dieter SM, et al. Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer. Cell Rep. 2021;36(3):109394. |
| 5H-Indeno[5,6-b]furan-3-acetamide, 6,7-dihydro-N-(5-methyl-2-thiazolyl)- Preparation Products And Raw materials |
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