Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl-

Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Suppliers list
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Products Intro: CAS:2102179-29-1
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G
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Products Intro: Product Name:TRPM8 antagonist 3
CAS:2102179-29-1
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Products Intro: Product Name:TRPM8 antagonist 3
CAS:2102179-29-1
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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Products Intro: Product Name:TRPM8 antagonist 3;TRPM8 antagonist 3,TRP Channel,Transient receptor potential channels,inhibit,TRPM-8 antagonist 3,Inhibitor
CAS:2102179-29-1
Purity:99.25% Package:1 mg;1 mL;10 mg;100 mg;25 mg;5 mg;50 mg
Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Basic information
Product Name:Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl-
Synonyms:Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl-;TRPM8 antagonist 3;TRPM8 antagonist 3,TRP Channel,Transient receptor potential channels,inhibit,TRPM-8 antagonist 3,Inhibitor
CAS:2102179-29-1
MF:C13H12N2O4S
MW:292.31
EINECS:
Product Categories:
Mol File:2102179-29-1.mol
Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Structure
Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Chemical Properties
Boiling point 579.7±60.0 °C(Predicted)
density 1.517±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka6.08±0.45(Predicted)
color Off-white to light yellow
Safety Information
MSDS Information
Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Usage And Synthesis
Biological ActivityTRPM8 antagonist 3 is a novel TRPM8 blocker with an IC50 value of 11 nM.
References[1]. Bianchini G, et al. Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through pKa and LogD Modulation. J Med Chem. 2021 Nov 25;64(22):16820-16837.
Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Preparation Products And Raw materials
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