Company Name: |
Shanghai Chaolan Chemical Technology Center
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Tel: |
QQ:65489617 15618227136 |
Email: |
info@SuperLan-chem.com |
Products Intro: |
Product Name:TRPM8 antagonist 3 CAS:2102179-29-1 Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:TRPM8 antagonist 3;TRPM8 antagonist 3,TRP Channel,Transient receptor potential channels,inhibit,TRPM-8 antagonist 3,Inhibitor CAS:2102179-29-1 Purity:99.25% Package:1 mg;1 mL;10 mg;100 mg;25 mg;5 mg;50 mg
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| Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Basic information |
| Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Chemical Properties |
Boiling point | 579.7±60.0 °C(Predicted) | density | 1.517±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | form | Solid | pka | 6.08±0.45(Predicted) | color | Off-white to light yellow |
| Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Usage And Synthesis |
Biological Activity | TRPM8 antagonist 3 is a novel TRPM8 blocker with an IC50 value of 11 nM. | References | [1]. Bianchini G, et al. Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through pKa and LogD Modulation. J Med Chem. 2021 Nov 25;64(22):16820-16837. |
| Methanone, [4-hydroxy-2-(2-hydroxyphenyl)-5-thiazolyl]-2-isoxazolidinyl- Preparation Products And Raw materials |
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