| Company Name: |
Apollo Scientific Ltd.
|
| Tel: |
44 161 406 0505 |
| Email: |
sales@apolloscientific.co.uk |
| Products Intro: |
Product Name:rHuG-CSF
Package:￡42.00/2μg;￡106.00/10μg Remarks:BITP1063
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
|
|
| | LENOGRASTIM Basic information |
| | LENOGRASTIM Chemical Properties |
| HS Code | 3504009000 | | Toxicity | dog,LD50,intravenous,> 5mg/kg (5mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 93, 1992. |
| | LENOGRASTIM Usage And Synthesis |
| Uses | Antineutropenic; hematopoietic stimulant. | | Metabolism | Lenograstim is primarily eliminated by the kidney and
neutrophils/neutrophil precursors; the latter presumably
involves binding of the growth factor to the G-CSF
receptor on the cell surface, internalisation of the growth
factor-receptor complexes via endocytosis, and subsequent
degradation inside the cells. During chemotherapy induced neutropenia, the clearance of lenograstim is
significantly reduced and the concentration of lenograstim
is sustained until onset of neutrophil recovery. |
| | LENOGRASTIM Preparation Products And Raw materials |
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