| Company Name: |
Princeton BioMolecular Research, Inc.
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| Tel: |
732 355 9920 ext. 102 |
| Email: |
info@princetonbio.com |
| Products Intro: |
Product Name:2,2-Diphenyl-propionic acid 2-diethylamino-ethyl ester
CAS:3563-01-7
Package:10g
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| | Diethylaminoethyl Basic information |
| Product Name: | Diethylaminoethyl | | Synonyms: | Diethylaminoethyl;aprofen;APROPHEN;2,2-Diphenylpropionic acid 2-(diethylamino)ethyl ester;2,2-Diphenylpropionic acid 2-diethylaminoethyl ester;α-Methyl-α-phenylphenylacetic acid 2-(diethylamino)ethyl ester;Benzeneacetic acid, α-methyl-α-phenyl-, 2-(diethylamino)ethyl ester;Aprofenum | | CAS: | 3563-01-7 | | MF: | C21H27NO2 | | MW: | 325.44 | | EINECS: | | | Product Categories: | | | Mol File: | 3563-01-7.mol |  |
| | Diethylaminoethyl Chemical Properties |
| Melting point | 161-162 °C | | Boiling point | 180-185 °C(Press: 2 Torr) | | density | 1.0500 g/cm3 | | pka | 9.20±0.25(Predicted) |
| | Diethylaminoethyl Usage And Synthesis |
| Originator | Aprofene,ZYF Pharm Chemical | | Manufacturing Process | 32 parts of α,α-diphenylpropionic acid chloride (made from diphenylpropionic
acid and thionyl chloride, B.P./12 mm 170°C) are mixed with 50 parts of
diethylaminoethanol. The mixture is heated for two hours to 150°-160°C. It is
then suspended in dilute hydrochloric acid. The solution is treated with ether.
After separation of the aqueous solution, the base is precipitated with sodium
hydroxide solution and suspended in ether.
After removal of the ether by distillation, the residue is distilled in a vacuum.
α,α-Diphenylpropionic acid β-diethylaminoethyl ester is obtained as a thick oil
by distilling under 2 mm pressure at 180°-185°C. It is readily soluble in
diluted acids. | | Therapeutic Function | Spasmolytic |
| | Diethylaminoethyl Preparation Products And Raw materials |
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