Company Name: |
Shanghai Lingfei Pharmaceutical Technology Co., Ltd
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Tel: |
15618928656 15618928656 |
Email: |
771909552@qq.com |
Products Intro: |
Product Name:4H-Pyrrolo[2,3-d]thiazole-5-carboxamide, N-[[2-(2-benzofuranyl)phenyl]methyl]- CAS:2310293-81-1 Purity:98% HPLC Package:1g;5g;10;25g;50g;100g;250g;500g;1315g
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| 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide, N-[[2-(2-benzofuranyl)phenyl]methyl]- Basic information |
| 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide, N-[[2-(2-benzofuranyl)phenyl]methyl]- Chemical Properties |
Boiling point | 707.6±60.0 °C(Predicted) | density | 1.394±0.06 g/cm3(Predicted) | pka | 11.90±0.30(Predicted) |
| 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide, N-[[2-(2-benzofuranyl)phenyl]methyl]- Usage And Synthesis |
Uses | Microtubule inhibitor 8 (MP-HJ-1b) is a potent inhibitor of microtubule. Microtubule inhibitor 8 triggers cell death through ferroptosis. Microtubule inhibitor 8 has anti-tumor effect[1][2]. | References | [1] Nannan Ning, et al. A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res. 2018 Oct 15;78(20):5949-5957. DOI:10.1158/0008-5472.CAN-18-0455 [2] Nannan Ning, et al. A novel microtubule inhibitor promotes tumor ferroptosis by attenuating SLC7A11/GPX4 signaling. Cell Death Discov. 2023 Dec 13;9(1):453. DOI:10.1038/s41420-023-01713-6 |
| 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide, N-[[2-(2-benzofuranyl)phenyl]methyl]- Preparation Products And Raw materials |
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