| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:IDO1-IN-15
CAS:2126853-17-4
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[(propylamino)carbonyl]amino]- manufacturers
- IDO1-IN-15
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- $1980.00 / 50mg
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2024-11-19
- CAS:2126853-17-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[(propylamino)carbonyl]amino]- Basic information |
| | 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[(propylamino)carbonyl]amino]- Chemical Properties |
| density | 1.75±0.1 g/cm3(Predicted) | | pka | 7.50±0.69(Predicted) |
| | 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[(propylamino)carbonyl]amino]- Usage And Synthesis |
| Uses | IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM). IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat[1]. | | IC 50 | IDO1: 127 nM (IC50) | | References | [1] Wu Y, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021;52:128373. DOI:10.1016/j.bmcl.2021.128373 |
| | 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[(propylamino)carbonyl]amino]- Preparation Products And Raw materials |
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