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| | FOSFOMYCIN SODIUM Basic information |
| Product Name: | FOSFOMYCIN SODIUM | | Synonyms: | [4-[(E)-4-(4-phosphonatooxyphenyl)hex-3-en-3-yl]phenyl] phosphate;tetrasodium (3E)-hex-3-ene-3,4-diyldibenzene-4,1-diyl bis(phosphate) | | CAS: | 23519-26-8 | | MF: | C18H18Na4O8P2 | | MW: | 516.237322 | | EINECS: | | | Product Categories: | | | Mol File: | 23519-26-8.mol |  |
| | FOSFOMYCIN SODIUM Chemical Properties |
| | FOSFOMYCIN SODIUM Usage And Synthesis |
| Originator | Stilphostrol,Dome,US,1955 | | Uses | Estrogen. | | Manufacturing Process | A solution of 1 part of α,α'-diethyl-4,4'-dihydroxystilbene in 5 parts of pyridine
is added drop by drop to the strongly cooled solution of 2 parts of
phosphorus-hydroxy chloride in 5 parts of pyridine. The mixture soon solidifies
to a crystalline magma. It is allowed to stand in ice for ? hour and then for
an hour at room temperature. The mass is then poured into an excess of
saturated sodium bicarbonate solution. Unconsumed parent material is
removed by extraction with ether. The aqueous solution is then mixed with 2
N hydrochloric acid, whereupon the primary phosphoric acid ester of α,α'-
diethyl-4,4'-dihydroxystilbene of the formula is precipitated in the form of a
voluminous white powder. By recrystallization or reprecipitation this ester may
be further purified.
| | Therapeutic Function | Estrogen, Antitumor |
| | FOSFOMYCIN SODIUM Preparation Products And Raw materials |
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