Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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Tel: |
0717-6449896 13886658719 |
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root@zhongyitai.com |
Products Intro: |
Product Name:Lactosylsphingosine (d18:1) CAS:109785-20-8 Purity:98+% Package:1mg
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| lactosyl lysosphingolipid Basic information |
Product Name: | lactosyl lysosphingolipid | Synonyms: | lactosyl lysosphingolipid;D-lactosyl-1-1'-D-erythro-sphingosine;2-[6-[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;Lactosylsphingosine (d18:1);Lyso-Lactosylceramide (synthetic);Lactosyl-C18-sphingosine;Lactosylsphingosine (d18:1) (synthetic);Lactosyl(ss) Sphingosine (d18:1) | CAS: | 109785-20-8 | MF: | C30H57NO12 | MW: | 623.77308 | EINECS: | | Product Categories: | | Mol File: | 109785-20-8.mol | ![lactosyl lysosphingolipid Structure](CAS/20181012/GIF/109785-20-8.gif) |
| lactosyl lysosphingolipid Chemical Properties |
Boiling point | 845.8±65.0 °C(Predicted) | density | 1.27±0.1 g/cm3(Predicted) | storage temp. | -20°C | solubility | Chloroform:Methanol:Water (2:1:0.1): soluble; DMSO: soluble; Water: soluble | form | A solid | pka | 11.74±0.45(Predicted) | BRN | 5680460 |
| lactosyl lysosphingolipid Usage And Synthesis |
Description | Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088] | Uses | Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column. | General Description | Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract. | Biochem/physiol Actions | Lactosyl sphingosine?exhibits better hemolytic activity than lysolecithin. |
| lactosyl lysosphingolipid Preparation Products And Raw materials |
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