| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:WR99210
CAS:47326-86-3
Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:W1770
|
|
| | BRL 6231 Basic information |
| Product Name: | BRL 6231 | | Synonyms: | BRL 6231;1-[3-[(2,4,5-Trichlorophenyl)oxy]propoxy]-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine;5-[3-(2,4,5-Trichlorophenoxy)propoxy]-6,6-dimethyl-5,6-dihydro-1,3,5-triazine-2,4-diamine;WR-99210;1,6-Dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine;6,6-dimethyl-1-(3-(2,4,5-trichlorophenoxy)propoxy)-1,6-dihydro-1,3,5-triazine-2,4-diamine;Antifolate,Inhibitor,Bacterial,WR 99210,inhibit,WR99210,WR-99210;1,3,5-Triazine-2,4-diamine, 1,6-dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]- | | CAS: | 47326-86-3 | | MF: | C14H18Cl3N5O2 | | MW: | 394.68 | | EINECS: | | | Product Categories: | | | Mol File: | 47326-86-3.mol |  |
| | BRL 6231 Chemical Properties |
| Boiling point | 519.7±60.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble0.2mg/mL, clear (warmed) | | form | powder | | pka | 8.48±0.40(Predicted) | | color | white to off-white |
| | BRL 6231 Usage And Synthesis |
| Biochem/physiol Actions | WR99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (DHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases. |
| | BRL 6231 Preparation Products And Raw materials |
|