PAR4 antagonist 1

PAR4 antagonist 1 Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:PAR4 antagonist 1 CAS:2173201-65-3 Package:10mg;50mg

PAR4 antagonist 1 Basic information

Product Name:	PAR4 antagonist 1
Synonyms:	PAR4 antagonist 1;Carbamic acid, N-(2-methyl-5-pyrimidinyl)-, [(7R)-5-fluoro-7,8-dihydro-2-(2-methoxy-7-methyl-5-quinoxalinyl)furo[2,3-g]benzothiazol-7-yl]methyl ester
CAS:	2173201-65-3
MF:	C26H21FN6O4S
MW:	532.55
EINECS:
Product Categories:
Mol File:	2173201-65-3.mol

PAR4 antagonist 1 Chemical Properties

density	1.461±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	11.46±0.70(predicted)

Safety Information

MSDS Information

PAR4 antagonist 1 Usage And Synthesis

Uses	PAR4 antagonist 1 (Compound 48) is a protease activated receptor 4 (PAR4) antagonist with an IC50 of 1.8 nM. PAR4 antagonist 1 has an IC50 of 2 nM against γ-thrombin-activated PAR4 in platelet-rich plasma (PRP). PAR4 antagonist 1 can be used in antithrombotic research[1].
IC 50	PAR4: 1.8 nM (IC₅₀)
References	[1] Zhang X, et al. Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis. J Med Chem. 2024 Feb 22. DOI:10.1021/acs.jmedchem.3c01986

PAR4 antagonist 1 Preparation Products And Raw materials

Tag:PAR4 antagonist 1(2173201-65-3) Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login