Company Name: |
SIGMA-RBI
|
Tel: |
800 736 3690 (Orders) |
Email: |
|
Products Intro: |
|
|
| Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Basic information |
Product Name: | Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF | Synonyms: | Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF;Anti-DCP1A (C-terminal) antibody produced in rabbit | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Chemical Properties |
| Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Usage And Synthesis |
Uses | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunofluorescence-cell culture cells (1 paper) | General Description | Dcp1 colocalizes with Dcp2 in distinct cytoplasmic foci along with other proteins involved in the 5′ to 3′ mRNA decay. These foci are termed PB (processing bodies) or DCP-bodies. Anti-DCP1A (C-terminal) is produced in rabbit using as immunogen a synthetic peptide corresponding to a sequence at C-terminal of human DCP1A conjugated to KLH. Two distinct genes of human DCP1 were identified, DCP1A and DCP1B, which share ~70% homology in their N-terminal and ~30% homology in their full length. | Biochem/physiol Actions | Dcp1 cleaves the m7G mRNA cap in the 5′ to 3′ mRNA decay pathway, in association with Dcp2 and Hedls complex. Decapping is a critical and highly regulated step in the turnover of mRNA which involves decapping enzymes that hydrolyze the cap structure at the 5′ mRNA. |
| Anti-DCP1 Decapping enzyme 1, homolog A, Anti-Smad 4-interacting transcription factor, Anti-Smad 4-interacting transcriptional co-activator, Anti-SMAD4IP1, Anti-SMIF Preparation Products And Raw materials |
|