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| | ANTI-CDC25A Basic information |
| Product Name: | ANTI-CDC25A | | Synonyms: | MONOCLONAL ANTI-CDC25A;ANTI-CELL DIVISION CYCLE 25A;ANTI-CDC25A;ANTI-CDC25A(144);ANTI-CDC25A, HUMAN;ANTI-CDC25A RABBIT PAB;Monoclonal Anti-Cdc25A antibody produced in mouse;Anti-CDC25a antibody produced in chicken | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CDC25A Structure]() |
| | ANTI-CDC25A Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| | ANTI-CDC25A Usage And Synthesis |
| General Description | The cell division cycle 25A (CDC25A) is a potent human oncogene, mapped to chromosome 3p21.31. The gene codes for a member of Cdc25 phosphatase family. | | Biochem/physiol Actions | Cell division cycle 25A (CDC25A) plays a crucial role at the Gl/S-phase transition. The protein also facilitates G2 arrest caused by DNA damage or in the presence of unreplicated DNA. CDC25A controls cell cycle progression by dephosphorylating and activating cyclin-CDK complexes. Elevated expression of the gene increases the G1/S and G2/M transitions, which subsequently lead to genomic instability and tumorigenesis. CDC25A expression might be associated with the pathogenesis and progression of hepatocellular carcinoma (HCC). |
| | ANTI-CDC25A Preparation Products And Raw materials |
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