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| CANDOXATRIL Basic information |
Product Name: | CANDOXATRIL | Synonyms: | 4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid;UK-79300;Candoxatril [usan:inn:ban];candoxatril;cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-Methoxyethoxy)Methyl]-3-oxopropyl]cyclopentyl]carbonyl]aMino]cyclohexanecarboxylic Acid;Cyclohexanecarboxylic acid, 4-[[[1-[(2S)-3-[(2,3-dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]-,cis-;Candoxatril
(UK 79300);4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid | CAS: | 123122-55-4 | MF: | C29H41NO7 | MW: | 515.63834 | EINECS: | | Product Categories: | Aromatics;Chiral Reagents;Pharmaceuticals;Inhibitors;Intermediates & Fine Chemicals | Mol File: | 123122-55-4.mol | ![CANDOXATRIL Structure](CAS/GIF/123122-55-4.gif) |
| CANDOXATRIL Chemical Properties |
Melting point | 107-109° | alpha | D -5.8° (c = 1 in methanol) | Boiling point | 718.4±60.0 °C(Predicted) | density | 1.21±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 4.84±0.25(Predicted) |
| CANDOXATRIL Usage And Synthesis |
Uses | Neutral endopeptidase inhibitor. Used in treatment of congestive heart failure. | Uses | Neutral endopeptidase inhibitor. Candoxatril is used in treatment of congestive heart failure. | Definition | ChEBI: The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart fa
lure. |
| CANDOXATRIL Preparation Products And Raw materials |
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