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| (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide Basic information |
Product Name: | (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide | Synonyms: | (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide;Laurepukine;Laurepukin | CAS: | 34029-94-2 | MF: | C18H17NO4 | MW: | 311.33188 | EINECS: | | Product Categories: | | Mol File: | 34029-94-2.mol | |
| (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide Chemical Properties |
Melting point | 230-231° | alpha | D -222° (c = 0.022 in chloroform) |
| (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide Usage And Synthesis |
Description | The alkaloid originally isolated under this name by Aston proved to be a
mixture of laureline and pukateine and the name was then given to a third alkaloid occurring in the bark of Laurelia Novae-Zelandae. The base crystallizes in
colOUrless needles or hexagonal tablets and is laevorotatory with [α]D - 222°
(CHCl 3 ). The sulphate hexahydrate, m.p. 99-l00°C is almost completely insoluble in H20; the methiodide has m.p. 249-250°C and the O,G-dimethyl
ether forms colourless prisms, m.p. l34°C, b.p. 200-2l0°C/l0 mm; [α]D - 314°
(CHC13). The probable structure, given above, has been deduced by comparison
with other, similar alkaloids although the alternative structure 3 :4-dihydroxy-
6:7-methylenedioxyaporphine, is not completely excluded. | References | Aston.,J. Chem. Soc., 97, 1381 (1910)
Barger, Girardet., Helv. Chim. Acta., 14, 481 (1931)
Girardet., ibid, 14, 504 (1931)
Govindachari et al., Chem. Ber., 91, 36 (1958) |
| (7R)-6,7,7aβ,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-12-ol 7-oxide Preparation Products And Raw materials |
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