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2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol

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2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Suppliers list
Company Name: SynphaBase AG  
Tel: +41 61 4674 333
Email: info@synphabase.ch
Products Intro: Purity:>95%
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Purity:98% (HPLC), powder
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Basic information
Product Name:2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol
Synonyms:2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol;PP242 hydrate
CAS:
MF:C16H16N6O
MW:308.33784
EINECS:
Product Categories:Heterocyclic Building Blocks
Mol File:Mol File
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Structure
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Chemical Properties
storage temp. 2-8°C
form powder
color off-white
Safety Information
WGK Germany 2
MSDS Information
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Usage And Synthesis
UsesPP242 hydrate has been used:
  • as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling
  • as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis
  • as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection

Biochem/physiol ActionsPP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Preparation Products And Raw materials
Tag:2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)1H-indol- 5-ol Related Product Information