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CP-547632

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CP-547632 Suppliers list
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:3-((4-bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide
CAS:252003-65-9
Purity:0.99 Package:1kg
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:CP-547632
CAS:252003-65-9
Purity:95-99% Package:1g;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:CP-547632
CAS:252003-65-9
Purity:98.51% Package:1mg;30USD|5mg;68USD|10mg;98USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:CP-547632 (PAN-90806)
CAS:252003-65-9
Purity:98% Package:10mg Remarks:V5272
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:CP-547632
CAS:252003-65-9
Purity:98.51% Package:1mg;30USD|5mg;68USD|10mg;98USD

CP-547632 manufacturers

  • CP-547632
  • CP-547632 pictures
  • $30.00 / 1mg
  • 2024-11-19
  • CAS:252003-65-9
  • Min. Order:
  • Purity: 98.51%
  • Supply Ability: 10g
  • CP-547632
  • CP-547632 pictures
  • $30.00 / 1mg
  • 2024-11-19
  • CAS:252003-65-9
  • Min. Order:
  • Purity: 98.51%
  • Supply Ability: 10g
  • CP-547632
  • CP-547632 pictures
  • $1.00 / 1g
  • 2020-01-13
  • CAS:252003-65-9
  • Min. Order: 1g
  • Purity: 95-99%
  • Supply Ability: 1ton
CP-547632 Basic information
Product Name:CP-547632
Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
CAS:252003-65-9
MF:C20H24BrF2N5O3S
MW:532.4
EINECS:200-258-5
Product Categories:
Mol File:252003-65-9.mol
CP-547632 Structure
CP-547632 Chemical Properties
Boiling point 548.6±50.0 °C(Predicted)
density 1.532
storage temp. 2-8°C
solubility DMSO: 94 mM
form A solid
pka12.50±0.70(Predicted)
color White to light yellow
Safety Information
MSDS Information
CP-547632 Usage And Synthesis
DescriptionCP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.
CP-547632 Preparation Products And Raw materials
Preparation ProductsCP-547632 (hydrochloride)
Tag:CP-547632(252003-65-9) Related Product Information
1,1-DIBROMOTETRAFLUOROETHANE α-Bromo-2,3,4,5,6-pentafluorotoluene