| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Largazole;Largazole
CAS:1009815-87-5
Purity:98% Package:5 mg
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| | Largazole Basic information |
| Product Name: | Largazole | | Synonyms: | Largazole;Octanethioic acid, S-[(3E)-4-[(5R,8S,11S)-5-methyl-8-(1-methylethyl)-6,9,13-trioxo-10-oxa-3,17-dithia-7,14,19,20-tetraazatricyclo[14.2.1.12,5]eicosa-2(20),16(19),18-trien-11-yl]-3-buten-1-yl] ester;AXESYCSCGBQJBL-SZPBEECKSA-N;(+)-largazole | | CAS: | 1009815-87-5 | | MF: | C29H42N4O5S3 | | MW: | 622.86 | | EINECS: | | | Product Categories: | | | Mol File: | 1009815-87-5.mol |  |
| | Largazole Chemical Properties |
| density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Storage at -20℃ | | pka | 12.12±0.70(Predicted) |
| | Largazole Usage And Synthesis |
| Uses | Largazole is a potent and selective histone deacetylase (HDAC) inhibitor. | | Uses | Largazole is derived from cyanobacteria that grow on coral reefs, which may have potentials as an anti-cancer drug. Largazole is a potent histone deacetylase inhibitor. [1] Largazole has its potent antiproliferative activity against a number of cancer cell-lines including MDA-MB-231 mammary cells (GI50 7.7 nM), U2OS fibroblastic osteosarcoma cells (GI50 55 nM), HT29 colon cells (GI50 12 nM), and IMR-32 neuroblastoma cells (GI50 16 nM). |
| | Largazole Preparation Products And Raw materials |
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