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| | 12-Lipoxygenase (platelet-type, mouse recombinant) Basic information |
| | 12-Lipoxygenase (platelet-type, mouse recombinant) Chemical Properties |
| | 12-Lipoxygenase (platelet-type, mouse recombinant) Usage And Synthesis |
| Description | 12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid.1 There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics.2 Leukocyte-type 12-LO has the ability to also produce 15-HpETE, however, platelet-type predominately forms 12-HpETE.2 Epidermal-type 12(S)- and 12(R)-LO enzymes have also been characterized, which catalyze the synthesis of their respective stereospecific 12-HETE products.2,3WARNING This product is not for human or veterinary use. |
| | 12-Lipoxygenase (platelet-type, mouse recombinant) Preparation Products And Raw materials |
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