| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:Ro 106-9920-d5;6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| | 6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Basic information |
| | 6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Chemical Properties |
| | 6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Usage And Synthesis |
| Uses | Labelled Ro 106-9920 (R637500). Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. |
| | 6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Preparation Products And Raw materials |
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