| Company Name: |
PharmaBlock Sciences (Nanjing), Inc.
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| Tel: |
4000255188 |
| Email: |
sun_dan@PharmaBlock.com |
| Products Intro: |
Product Name:WAY-255348
CAS:872141-23-6
Purity:97% Package:1G;5G;10G;100G;250G
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:WAY-255348
CAS:872141-23-6
Purity:详情请点击官网 Package:1 mg
|
|
| | WAY-255348 Basic information |
| Product Name: | WAY-255348 | | Synonyms: | WAY-255348;5-(7-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile;1H-Pyrrole-2-carbonitrile, 5-(7-fluoro-2,3-dihydro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methyl-;5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methy l-1H-pyrrole-2-carbonitrile | | CAS: | 872141-23-6 | | MF: | C16H14FN3O | | MW: | 283.3 | | EINECS: | | | Product Categories: | | | Mol File: | 872141-23-6.mol |  |
| | WAY-255348 Chemical Properties |
| Boiling point | 467.1±45.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | pka | 12.77±0.40(Predicted) |
| | WAY-255348 Usage And Synthesis |
| Description | WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways. |
| | WAY-255348 Preparation Products And Raw materials |
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