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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
Products Intro: |
Product Name:1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine CAS:1380088-03-8 Package:100Mg,25Mg,50Mg
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Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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Products Intro: |
Product Name:KB SRC 4 CAS:1380088-03-8 Purity:98% by HPLC Remarks:KB SRC 4 is a cell-permeable, potent and highly selective c-Src inhibitor with Kd value of 86 nM and Ki value of 44 nM, which is a key signaling kinase in cancer. It displays no inhibition on c-Abl up
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| 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine Basic information |
Product Name: | 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine | Synonyms: | 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;KB SRC 4;KB SRC 4
(c-Src-IN-4);1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[3-[1-([1,1'-biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)- | CAS: | 1380088-03-8 | MF: | C32H23ClN8 | MW: | 555.03 | EINECS: | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors | Mol File: | 1380088-03-8.mol | |
| 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine Chemical Properties |
Boiling point | 789.2±70.0 °C(Predicted) | density | 1.39±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble to 20 mM in DMSO | form | Powder | pka | 3.46±0.30(Predicted) | color | Light brown to brown |
| 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine Usage And Synthesis |
Uses | 1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a highly selective and cell permeable c-Src kinase inhibitor. c-Src is a a key signaling kinase in cancer and this compound shows promising therapeutic potential, significantly more so than pan-kinase inhibiitors, in the treatment of cancers. | storage | Store at +4°C |
| 1-[3-[1-([1,1'-Biphenyl]-3-ylMethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine Preparation Products And Raw materials |
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